Four Specialized Handpieces
AGNES Ultra was built for flexibility. Click any handpiece to explore its technology, applications, and clinical evidence.
AGNES Ultra Cannula
The AGNES Ultra Cannula is a hemi-insulated RF electrode that delivers focused or precise unidirectional radiofrequency energy beneath the skin — directly to subdermal tissue. Unlike surface-level treatments, the Cannula works from the inside out, achieving access to subdermal tissue beyond the reach of topical treatments.
Available in 18G · 20G · 23G

Insulated Side
Protects overlying skin & dermis
Active RF Side (10mm)
Delivers energy to target tissue below

Procedural Applications
- ✓Dermatologic procedures requiring electrocoagulation
- ✓General surgical procedures requiring hemostasis
- ✓Procedures benefiting from precise subdermal energy delivery
- ✓Cases where focused, unidirectional RF delivery is indicated
Why AGNES Ultra?
- ›10+ years of clinical investigation & peer-reviewed data
- ›Developed by a board-certified dermatologist
- ›Proprietary partial insulation for unmatched tissue control
- ›Multi-modality platform — not a single-indication device
- ›Unrivaled safety profile backed by published clinical evidence
AGNES Ultra Cannula is intended for use by trained medical professionals only. Results may vary.
Polygonal Microblade Technology
Unlike conventional round needles, the Trace (F) uses a polygonal microblade geometry that distributes RF energy more evenly across the treatment zone. This results in more consistent heating, reduced hot spots, and superior structural remodeling in delicate facial areas such as the periorbital region, nasolabial folds, and jawline.
- More uniform RF energy distribution vs. cone-shaped needles
- Reduced hot spots for safer, more predictable outcomes
- Superior structural remodeling in delicate facial zones
- Precision targeting of periorbital, nasolabial, and jawline areas

Polygonal blade vs. cone-shaped needle: more evenly distributed energy delivery
AGNES Ultra in the Real World
Click any video to watch full screen. Hear directly from providers and see the technology in action.
Clinically Proven Results
Patient Satisfaction
Visible reduction in submental fullness and improved jawline definition after 3 treatments
Journal of Cosmetic Dermatology, 2023
Provider Satisfaction
Superior outcomes when combining multiple handpieces for layered treatment approach
Aesthetic Surgery Journal, 2024
Frequently Asked Questions
Everything you need to know about AGNES Ultra RF microneedling
Real Patient Results
Clinical photography showing visible improvements in skin texture, contour, and overall rejuvenation. Click any image to enlarge.
Pair With 
PlazMagik's low-intensity cold atmospheric plasma is designed to complement RF-based workflows — not compete with them. Add it as a finishing step and create new treatment opportunities within your existing patient base.
Post-Treatment Finishing Step
Apply PlazMagik after RF sessions to support the skin's recovery environment and extend the value of post-treatment topicals.
Topical Protocol Enhancement
Incorporate as a final step in finishing protocols — helping post-treatment serums and recovery products work harder.
Low-Downtime Add-On
Minimal setup and a non-contact delivery make PlazMagik an easy bundle or upsell addition to existing appointments.
PlazMagik is FDA 510(k) cleared · Dual-gas cold atmospheric plasma (He + Ar) · Non-contact delivery
Complete Your Protocol
Explore the Full Agnes Medical Collection
Each Agnes Medical technology is designed to complement the others — combine them to build comprehensive, differentiated treatment protocols.


Targeted Precision. Proven Results.
The original targeted RF microneedling platform — clinically validated for facial sculpting, acne treatment, and subdermal tissue remodeling with unmatched precision.


Dual Gas Plasma Technology.
FDA 510(k) cleared dual-gas cold atmospheric plasma (He + Ar). A non-contact finishing step that generates reactive molecules to support skin regeneration.


Microbiome-Based Skin Renewal.
Formulated with research-backed L. paracasei nanovesicles, LactoReborn bridges professional skincare with regenerative biology for visible, lasting results.

